The mechanism of activation of the first component of complement by a univalent hapten-IgG antibody complex.
نویسندگان
چکیده
منابع مشابه
Complement activation by a univalent hapten-antibody complex.
The univalent hapten, nonadeca lysyl epsilon-Dnp-lysine, binds tightly to rabbit anti-2,4-dinitrophenyl antibody, and the complex has a sedimentation coefficient of 6.7, characteristic of a single antibody molecule. In this communication, we show that this complex is a good activator of the serum complement system. For activation to occur, the univalent hapten must contain the specific group wh...
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ورودعنوان ژورنال:
- Journal of immunology
دوره 118 6 شماره
صفحات -
تاریخ انتشار 1977